Compounded Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on the pineal peptide epithalamin, explored for circadian rhythm, sleep, and cellular longevity. Prescribed online by US-licensed doctors and dispensed by state-licensed compounding pharmacies.
- Nightly subcutaneous injection in short cyclical courses
- Compounded by state-licensed pharmacies
- Studied for circadian, antioxidant, and telomere-related pathways
- No insurance required
shipping
doctors
doctor 24/7
- Same price at every dose. No hidden fees.
- Free expedited shipping.
- No membership fees.
- Doctor-led plans, ongoing doctor support.
Why do people explore epitalon therapy?
Explore circadian support, antioxidant defense, and longevity pathways — with honest, evidence-aware expectations.
Sleep & Circadian
- May support melatonin rhythm
- Steadier sleep timing
- Pineal signaling focus
Cellular Longevity
- Telomere pathway (in vitro)
- Healthy-aging interest
- Cyclical, low-burden dosing
Antioxidant Defense
- Antioxidant enzymes (animal data)
- Oxidative-stress focus
- Neuroendocrine support
Healthy Aging
- Longevity-oriented protocol
- Doctor-guided courses
- Evidence-aware framing
Age well on your terms.
Compounded epitalon is explored for circadian rhythm, antioxidant defense, and cellular longevity — with measured, evidence-aware expectations.
Epitalon is a synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly), a defined version of the peptide epithalamin originally drawn from the pineal gland. It is studied as a bioregulator of circadian and neuroendocrine signaling that declines with age.
Because much of the evidence is preclinical or from small early studies, epitalon is best approached as an investigational longevity peptide that may support circadian and cellular-aging pathways — not a proven cure. A balanced, science-based approach to longevity.
Complete a quick online health intake
STEP
1
Share your health profile online. A US-licensed doctor reviews your fit and decides whether peptide therapy is right for you.
Receive your prescription at your door
STEP
2
If approved, your custom prescription ships free and overnight in temperature-controlled packaging, arriving safely at your home.
Get continuous care from your doctor
STEP
3
Message your care team with response, side-effect, medication, refill, route, or pharmacy questions so the plan can be reassessed as needed.
Why choose Peptide12?
Patients pick us for clinical rigor, transparent pricing, and care that doesn’t disappear after checkout.
FDA-registered pharmacies
Every prescription is compounded by FDA-registered 503A/503B pharmacies. Batch testing and certificates of analysis available on request.
US-licensed doctors
MDs licensed in your state, not just an order form. Your doctor titrates dosing and answers messages directly.
Transparent pricing
One flat price per protocol. No membership fees, no insurance hassle, no surprise charges. HSA and FSA accepted. Cancel anytime.
Care that doesn’t disappear
Message your doctor through your patient portal whenever you need to. Most replies within hours, never longer than 24.
What patients ask about
Patient feedback on clinician review, pharmacy sourcing, follow-up, and practical support.
Individual experiences vary and do not guarantee eligibility, prescription approval, symptom improvement, or a specific result.
“I went in skeptical and the doctor was refreshingly honest that a lot of the evidence is early. I run short courses twice a year and my sleep timing feels steadier. No hype, just a clear plan.”
Daniel R.
Austin, TX
“I like the cyclical approach — ten days on, then a long break, instead of another daily pill. The intake actually screened me carefully before approving anything.”
James T.
Boulder, CO
“My main goal was sleep and circadian support as I got into my fifties. A couple of courses in, I fall asleep on a more consistent schedule. They set realistic expectations up front.”
Mark H.
Charlotte, NC
“What sold me was how measured they were — no promises about reversing aging, just the pathways it may touch and the limits of the research. Cold-chain shipping and a sealed, batch-labeled vial.”
Lisa M.
Denver, CO
“I appreciated that the doctor flagged the cancer-history screening before anything else. Felt like a real clinic that takes the unknowns seriously, not a peptide vending machine.”
Karen S.
Phoenix, AZ
“Easy subcutaneous injection, overnight shipping, same-day answers from my care team. I treat it as part of a broader longevity routine rather than a miracle, which is exactly how they framed it.”
Ryan W.
Tampa, FL
Frequently asked questions
Supporting Studies
- 1.Khavinson et al. — Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells (Bull Exp Biol Med, 2003) — in vitro study
- 2.Araj et al. — Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties (Int J Mol Sci, 2025) — narrative review
- 3.Korkushko et al. — Effect of peptide preparation epithalamin on circadian rhythm of epiphyseal melatonin-producing function in elderly people (Bull Exp Biol Med, 2004) — small human study
- 4.Anisimov et al. — Inhibitory effect of the peptide epitalon on spontaneous mammary tumors in HER-2/neu transgenic mice (Int J Cancer, 2002) — preclinical animal study
- 5.Anisimov et al. — Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice (Biogerontology, 2003) — preclinical animal study
- 6.FDA — Pharmacy Compounding Advisory Committee notice of meeting; establishment of a public docket (Federal Register, 2026)