Educational graphic advising patients to plan maintenance with clinician follow-up before stopping GLP-1 medication.

2026-05-169 min readGLP-1 & weight loss

What happens when you stop GLP-1 medication?

Stopping a GLP-1 medication can lead to appetite return, weight regain, and loss of some cardiometabolic improvements for many people. Learn what to discuss with a clinician before tapering, pausing, or stopping semaglutide, tirzepatide, Wegovy, Ozempic, Zepbound, or Mounjaro.

Ready to start your protocol?

Free clinical review by a US-licensed doctor. Usually within 24 hours.